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reduced GABA signaling is linked to heightened anxiety Serotonin and dopamine influence mood regulation and motivation Glutamate drives excitatory signaling that, in excess, can fuel overactive stress circuits Chronic stress can also trigger low-grade neuroinflammation, a process increasingly tied to both anxiety and depression in clinical studies

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A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing

In addition to identifying priority areas for further research, it aims to improve the accessibility and usefulness of current knowledge for clinicians and researchers by combining biochemical, clinical, and lifestyle evidence into a cohesive narrative