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But there is a third modality by which they work, which I think is really important, which is that they actually have direct metabolic and metabolic inflammatory effects in the body
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Possible downsides include nausea, constipation, fatigue, and appetite rebound if stopped too quickly
Patients often have a personal goal they want to meet, but the medication may not be enough to reach that goal. Patients often approach treatment with a specific goal in mind a target weight or a certain rate of loss that may not align with what the medication is able to deliver on its own
Clinical evidence specifically comparing dual semaglutide-tirzepatide use to tirzepatide monotherapy remains limited because tirzepatide itself is already a dual-receptor agonist
