Common adverse effects , particularly during dose escalation, include: Nausea (reported by 2050% of patients, usually mild to moderate) Vomiting, diarrhoea, or constipation Abdominal discomfort or bloating Reduced appetite (therapeutic effect, but may feel unusual initially) Fatigue or headache These effects typically diminish over several weeks as tolerance develops
Nutr Res 32(9):701708 Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM (2001) C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
10.1016/j.mce.2016.04.020 260 ZhaoC.ZhangH.LiH.LvC.LiuX.LiZ.et al (2017)
Allow the vial and the bacteriostatic water to reach room temperature, swab both rubber stoppers with alcohol, then inject the diluent slowly down the inner glass wall rather than onto the lyophilised cake, and swirl gently until fully dissolved
What some people lose on a GLP-1 course compresses years of that process into a single treatment window
A: People with prediabetes or diabetes are generally eligible to donate blood, platelets and plasma if they are feeling well on the day of their donation