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A protocol should still reflect the study model, the schedule burden, and the monitoring plan
Symptoms of Psoriatic Arthritis The most common symptoms of psoriatic arthritis include: Swollen, stiff, and painful joints, particularly in the fingers and toes Foot pain and lower back pain Fatigue and morning stiffness Swelling and pain around tendons Reduced range of motion Nail changes, such as pitting or separation from the nail bed Eye redness and pain (uveitis) Scaly skin patches, especially on the knees, elbows, and scalp Causes and Risk Factors The exact cause of psoriatic arthritis is unknown, but several factors may play a role, including: Genetics: Having a family history of psoriasis or psoriatic arthritis increases the risk Infections: Certain infections, such as strep throat, may trigger the immune system Physical trauma: Injury to a joint or bone may increase the likelihood of developing PsA Obesity: Being overweight or obese is a risk factor for both psoriasis and psoriatic arthritis Diagnosis and Treatment To diagnose psoriatic arthritis, your doctor will review your medical history, perform a physical examination, and may order imaging tests (X-rays, MRIs, or ultrasounds) and blood tests
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