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In addition, nicotinamide, the primary NNMT substrate 95,96 , is broken down by Lactobacillus arabinosis into nicotinic acid and ammonia 56

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Both redoxins are also known to have anti-apoptotic properties through interactions with several transcription factors and proteins, such as inhibition of the MAPK cascade by binding to ASK-1 in their reduced state 24,35

doi: 10.1007/s00394-015-0838-9