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According to Jonathan Kaplan, MD, a board-certified plastic surgeon and GLP-1 expert at Pacific Heights Plastic Surgery in San Francisco, while constipation is not the most common side effect of Ozempic, some patients may experience less frequent bowel movements than usual while on the medication
Psychosocial Impact The normalization of semaglutide use for cosmetic weight loss is exacerbating body image issues, particularly among youth and women
Semaglutide uses a gradual titration approach, starting at a low dose and increasing over time
The STEP 1 trial (published in the New England Journal of Medicine) documented mean weight reductions of 14.9% with once-weekly semaglutide 2.4 mg compared to 2.4% with placebo, with corresponding improvements in waist circumference of approximately 13.5 cm with semaglutide versus 4.1 cm with placebo after 68 weeks
In another study, Saber et al
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