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While the redundancies we have discussed are primarily thought to act in the GSCs and their ability to remain GSCs or enter a pathway to differentiation, it is also possible that redundancies may exist in controlling the behavior of the other cells in the progenitor zone (those completing mitosis and those in meiotic S phase), which could impact over-proliferation and under-proliferation phenotypes
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TB-500 binds to actin monomers and promotes something called actin polymerization
However, the total impact could be much larger
In children with acute overwhelming illness and progressive neurological deterioration plasma ammonia measurement should be included in the urgent diagnostic work-up
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