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[PubMed] [Wiley] [PubMed] 104
Collectively, these recent contributions argue that future GSH-centric redox sensing and nanomedical approaches should (i) incorporate organelle targeting (especially mitochondria) to exploit subcellular redox heterogeneity, (ii) embed analyte-responsive activation into both therapeutic and imaging components, (iii) combine biochemical sensing with optical or thermal engineering for spatiotemporal control, and (iv) favor clinically translatable carriers (e.g., PLGA) for delivery
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Research has focused on three primary domains related to ferroptosis in OA: iron homeostasis, lipid metabolism, and the antioxidant defense mechanism
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