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On a cellular level, B12 serves as an essential cofactor for two key enzymatic reactions involving methionine synthase and methylmalonyl-CoA mutase

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133 Another randomized controlled trial in 57 subjects undergoing evaluation for male infertility found taking an oil providing 990 mg DHA and 135 mg EPA daily for 10 weeks decreased sperm DNA fragmentation and increased seminal antioxidant status more than a sunflower oil placebo, but did not affect other sperm parameters

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