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Retatrutide also produced clinically meaningful improvements in nonhigh-density lipoprotein cholesterol, triglycerides, and systolic blood pressure, a cardiovascular risk profile that pharmacists managing complex cardiometabolic patients will want to note

But Bent says recent research has shown higher levels dont necessarily equate to improved health outcomes

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doi: 10.3389/fphar.2025.1610512 Received 12 April 2025 Accepted 15 May 2025 Published 30 May 2025 Volume 16 - 2025 Edited by Karuna Rasineni, University of Nebraska Medical Center, United States Reviewed by Asher Rajkumar Rajan, University of Nebraska Medical Center, United States Akash Batta, Dayanand Medical College & Hospital, India Updates Copyright 2025 Li, Huang, Wang, Huang, Luo and Huang

Some patients report intermittent nausea that comes and goes, especially with dose increases or dietary changes

Useful for patients who want a non-injectable option