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A DSM study from the human nutrition and health department (59) describes hydroxytyrosol as the most powerful anti-inflammatory compound among polyphenols of olive oil, showing effective inhibition in the production of NO and PGE2, decreasing secretion of cytokines (IL-1, IL-1, IL-6, IL-12, TNF-) and chemokines (CXCL10/IP-10, CCL2/MPC-1) and reducing gene expression of iNOS, IL-1, CXCL10/IP-10, MIP-1, matrix metaloproteinase-9, and prostaglandin E2 synthase (PGES)

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It might increase the risk of developing diseases like lupus, celiac disease, and rheumatoid arthritis

PubMed laboratory research record [PMID: 23910417] PubMed record related to this compound for laboratory literature review

[68,69] This effect of GSH on skin pigmentation was reported half a century ago, with black human skin shown to exhibit lower levels of GSH than white skin

Each needle puncture dulls the tip and introduces potential contamination from the previous injection site