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Understanding why it happens can help people make more informed decisions about their medical treatments and seek out alternatives that may be less likely to trigger nausea

Test compounds were incubated in enriched 3-6 hpi ring-stage artemisinin resistant (Cam3.II R539T , Cam3.II C580Y and MRA1240) or sensitive (Cam3.II REV and MRA1239) parasites and the level of peroxide activation determined by measuring the percentage of intact compound remaining as a function of time (Fig 3A, B and D)

Mechanism and substrate recognition of human holo ACP synthase

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