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Behavioral observations For experiment 1: Antagonism of serotonergic behavior induced by the 5-HT 1A -receptor agonist ()-8-OH-DPAT: Dose response and efficacy of oral treatment with Atlas987 rats were placed in the observation cage immediately after treatment with () - 8-OH-DPAT and their behavior was scored for 60 min

We know due to side effects the higher dose may not be always suitable

The trade-off is real

Later in 2023, a multisociety statement from gastroenterology and hepatology organizations, including the AGA, AASLD, ACG, ASGE, and NASPGHAN, advised against routine discontinuation and emphasized individualized risk assessment [9]

Wegovy is contraindicated with a personal/family history of medullary thyroid carcinoma (MTC) or MEN 2

In the animals, the fetal complications happened when mothers did not gain weight or lost weight during their pregnancies