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Based on these early studies, induction of apoptosis and autophagy, cell cycle arrest, alterations in the cellular proliferation response and cell signaling, oxidative stress and changes in gene expression have all been proposed as contributing factors
For each animal, ten randomly selected fields were assessed, and the mean score was calculated to represent the group value
What is the typical weight loss with AOD-9604
this resulted in a reduction in body weight and corrected dyslipidaemia in several mouse models of obesity [102]
[see Dosage and Administration (2.2)]
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