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Abrupt discontinuation of opioids or administration of opioid antagonists (such as naloxone (NAL)) markedly increases norepinephrine release and triggers systemic withdrawal symptoms [14]

7.4 Fluorescent probe-based imaging markers At present, the most common fluorescence probe targets for PD biomarkers include -Syn, type B monoamine oxidase (MAO-B), dopamine-associated proteins (DATs and DARs), metal ions, ROS clusters, etc

Endogenous GHK-Cu concentrations in blood plasma are approximately 200ng/mL in young adults and decline significantly with age, which has driven research interest in its potential roles in tissue maintenance and repair

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