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More comprehensive human studies are needed to validate and fully understand these benefits

294 , F414F422 (2008)

In the primary analysis using the trial product estimand, which evaluated participants who adhered to treatment, bodyweight decreased progressively in all active treatment groups over the 26-week period, without clear evidence of reaching a plateau

glycerol and non-esterified fatty-acid release

For lumbar herniations, this typically means injecting in the lower back area on either side of the spine

The preclinical safety data is reassuring, with no significant adverse effects in animal studies at doses well above therapeutic ranges, but human long-term data does not exist