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Kita, K., Nakajima, S

Steinberg, D

Although its often spoken about as one thing, its consequences look different depending on the organ system involved: Metabolic organs (liver, adipose tissue, pancreas): Chronic inflammation here is associated with insulin resistance, higher glucose, and fatty liver disease. Blood vessels / cardiometabolic system: Inflammation contributes to long-term cardiovascular risk, and GLP-1 therapies improve several cardiometabolic risk factors, including blood pressure. Kidneys: Metabolic stress accelerates kidney damage and albuminuria

The study had several limitations, including a small sample size and an all-male participant group, making it difficult to draw broad conclusions, she says

As this promising treatment for weight loss works toward FDA approval, it is not yet available via standard prescription

MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road