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Here, we document the efficacy of such unimolecular GLP1 multi-agonists, and particularly the superiority of the GLP1/E conjugate, in managing the metabolic complications of PCOS in two mouse models of the disease, with evidence also for improvement of reproductive traits in an ovulatory model of PCOS

Sorli et al

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Clinically, steady state often correlates with a stabilization of side effects

Available from Accessed 20 Jun 2022 Janssen (2020) Prescribing information for INVOKANA

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