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Strategy Matters More Than the Drug: Both medications can lead to significant weight loss, but without a plan (strength training, nutrition, tapering off), users risk muscle loss, metabolic slowdown, and regaining weight later.

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Finally, sirtuin 1 (SIRT1) has the potential to become a treatment strategy for T2DM

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It also indirectly increases insulin sensitivity in skeletal muscle by promoting microvessel recruitment, which may enhance local insulin action [69]

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