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Doses of 5 to 10 nmol/kg/day were administered via subcutaneous injection just before the start of the dark cycle

Myocilin is involved in NgR1/Lingo-1-mediated oligodendrocyte differentiation and myelination of the optic nerve

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These models are validated by their ability to reproduce a diversity of new experimental results, and can be used as platforms for in-silico experimentation to determine the underlying mechanisms that give rise to the behavior seen in the clinic and experiments

They may work less effectively than injections for others

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