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the lysosomal protease inhibitor leupeptin slowed ferritin turnover and also delayed meningococcal replication (Larson et al., 2004)

TRAF6-mediated SM22 K21 ubiquitination promotes G6PD activation and NADPH production, contributing to GSH homeostasis and VSMC survival in vitro and in vivo

WONDERS 2 was terminated in April 2026, while WONDERS 1 remains on clinical hold under ongoing safety follow-up