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For people with genetic variants that cause more of an impact on CYP1B1 upregulation combined with an inability to eliminate the estrogen metabolites fast enough (due to phase II genes, diet, and lifestyle) then cigarette smoking is going to significantly increase the bad estrogen metabolites

I try to drink 8-10 glasses daily to help my body flush out toxins

For people following a plant-based diet that choose to exclude animal products, it can be difficult to get enough B12

Samaneh Y, ShahidehJahanian S, Azadeh M, Anoshirvan K

This complex is what interacts with cellular receptors and influences gene expression for tissue repair

But I think just because you can focus on one thing, you can really miss out