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Combining compounds also compounds uncertainty: interaction data in humans is limited, and the absence of large trials means dosing conventions are largely empirical rather than evidence-based

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it's also about adhering to the product's intended purpose

Patients should inform their healthcare provider of all medications they are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, to assess any potential interactions

For instance, we have recently reported that only 2 weeks of high fat diet (HFD) significantly altered contractile functions of the oxidative skeletal muscle soleus in young rats, although the same result could not be observed in the glycolytic extensor digitorum longus (EDL) muscle (Andrich et al., 2018b)