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Here, we find that semaglutide engages both G s and G q -dependent signalling pathways in Glp1r -expressing neurons in the area postrema (AP Glp1r ), the primary site of semaglutide action in the brain, and differentially regulates neuronal activation across distinct neuronal clusters

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The peptide works in cell culture

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Where BPC-157 and TB-500 reduce localized inflammation as a side effect of their primary regenerative actions, KPV acts as the designated anti-inflammatory driver

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