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In primary culture of satellite cells, the LASSS-treated HGF (Figure 1f, bars 9 and 11 , at 5 ng/ml without or with exposure to peroxynitrite, respectively) normally activates satellite cells to a level equivalent to the positive control ( bar 2 ) as revealed by BrdU-incorporation assay

By upregulating vascular endothelial growth factor (VEGF), BPC-157 promotes the formation of new capillaries in damaged tissues

Outcome measures include biomechanical tensile strength testing of repaired tissue, histological scoring of collagen fiber organization, and immunohistochemical staining for fibroblast and endothelial cell markers

Expect 15 to 30 percent improvement, mostly in softening the scar edges rather than filling the depth

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Oxidation and enhanced energy expenditure appeared to be vital in the proposed action of the peptide