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Semaglutide can cause nausea, vomiting, reduced appetite, and lower fluid intake in some people

Furthermore, a real-world retrospective study comparing the compliance of patients receiving different GLP-1RAs for the treatment of hyperglycemic found that even if GLP-1RA weekly preparations were used, there were still differences in compliance [171]

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As a result, the patenting of these broader sets of compounds disincentivize and block competitors from developing them as potential products