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Natsvlishvili N, Goguadze N, Zhuravliova E, Mikeladze D
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Results GLP-1R trafficking controls pharmacological insulin release Interaction between the surface regions of receptor transmembrane helices and the agonist N-terminus is critical for the activation of class B GPCRs, including the GLP-1R 20
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More important than my observation is the following: In comments by Thompson and Sturmer published in the journal Diabetes Care in 2023, about a study of GLP-1s and the risk of thyroid cancer conducted by Bezin et al which was published in the same journal issue, Thompson and Sturmer conclude that Thyroid cancer is a rare outcome, however, and the potential increase in absolute risk is very small
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