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After being washed with cold PBS, the spheroids were stained with Calcein AM/PI Cell Viability Kit (Beyotime)

In summary, PGC-1 emerges as the pivotal regulator in orchestrating the transcriptional cascades of mitochondrial biogenesis and modulating the expression level or activation degree of PGC-1 represents a potent strategy to finely regulate the intricate process of mitochondrial biogenesis

Traditional weight loss approaches, including caloric restriction and exercise, reduce both visceral and subcutaneous fat simultaneously

Collagen: 50 mg

Elevated liver enzymes usually indicate inflammation or injury of the liver

Data are shown as means standard errors (SE)