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In vitro, we found that in PSCs, high ROS accumulation attributed to high glucose was associated with PSC activation, which was characterized by increased expression of -SMA, accelerated migration, and increased synthesis of ECM proteins such as collagen I, all of which were rescued by GSH treatment
The intact cells and cell-free extract of strain ME-3 showed different potent antioxidative effects due to the expression of the antioxidant enzymes such as Mn-SOD and the components of the complete glutathione system (GSH, glutathione peroxidase and glutathione reductase)
2 Can the Rehydrate IV help with heat exhaustion
The DNA dot-blot showed the same trend in GSH deficiency and showed increased 5-mC levels with decreased 5-hmC levels (Fig
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