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It traverses the cell membrane through amino acid transporters, ASCT2 (alanine, serine, cysteine transporter 2), and system N transporter SN2 [34]
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Depression, also called major depressive disorder or clinical depression, is the most prevalent mood disorder in the United States and the world, affecting 8-10 percent of the general population at any given time, with every fourth person likely to experience the condition over the course of a lifetime
From this preliminary screening, we selected 43 compounds that showed at least 50% inhibition in all three assays for further doseresponse studies (Supplementary Tables 26)
Oxidative phosphorylation is organized in a series of subsequent steps involving several redox centers distributed in five protein complexes embedded in the IMM (Sun et al., 2013
Nat Commun (2019) 10(1):1617
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