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To truly understand the power of GLP-1s, we need to look at their relationship with key bodily functions: Delayed Gastric Emptying (The "Satiety Signal"): GLP-1 medications slow down how quickly food leaves your stomach
L.Gomez ValderasE.et al
doi: 10.3390/horticulturae5040067 30 FukaoT.Barrera-FigueroaB
This raising of GFR is also seen with glucagon agonists and is under investigation right now in multiple clinical trials
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Key takeaways Animal studies show BPC-157 improves gastric motility and protects against gastric damage in rats No human clinical trial has tested BPC-157 for gastroparesis specifically BPC-157 modulates the nitric oxide system and may interact with vagal nerve function, both relevant to gastroparesis Oral administration (250-500 mcg daily) is preferred over injection for GI-targeted effects BPC-157 is unusually stable in stomach acid, making oral delivery viable Patients should work with their gastroenterologist before adding BPC-157 to their gastroparesis management What is gastroparesis and why is it hard to treat
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