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By leveraging SFNs ability to induce oxidative stress and deplete thiol levels in parasites, this approach can enhance the efficacy of artemisinin and potentially restore its effectiveness against resistant strains
In more stubborn conditions, it can last 8 to 12 weeks, followed by a break
doi: 10.1007/s00415-019-09652-y 306 XueY
Most of the studies focus on the effect of NAC on cells and animal models with a notable absence of comprehensive clinical trial data which would lead to unknown biological effects and human health risks, thereby impeding its clinical application
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