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The pharmacokinetics of tirzepatide after a single 5 mg dose was evaluated in patients with different degrees of renal impairment (mild, moderate, severe, ESRD) compared with subjects with normal renal function

The molecule is classified as a triple receptor agonist, which means it interacts with the glucagon like peptide 1 receptor (GLP 1R), glucose dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GCGR)

It has an extensive safety track record and remains one of the most studied weight loss medications available

Diabetes Care 32 , 8490 (2009)

If you can reconstitute one, you can reconstitute the other

It also influences appetite and the speed with which food is digested