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Oral administration of liposome-embedded SOD (L-SOD) could ameliorate oxidative damage and inflammatory responses via inhibition of myeloperoxidase (MPO) and pro-inflammatory cytokines, as well as protect gut barrier function by promoting the expression of the tight junction proteins occludin and zonula occluden (ZO)-1 in the colon 750
& Versi, E
doi:10.1016/j.cjca.2014.12.019
G-CSF receptor-associated Janus kinase 1/2 (JAK1/2) rapidly activate the mitogen-activated protein kinase (MAPK) and phosphoinositide 3-kinase (PI3K) signaling pathways 39,99 and phosphorylate signal transducer and activator of transcription family member 3 (STAT3), causing them to translocate into the nucleus to facilitate the transcription of target genes
*Correspondence: Chao Wang, [email protected]
Trends Cancer 7 , 891901 (2021)
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