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Clinical translation would require trials in cardiac patient populations with appropriate safety monitoring given theoretical concerns about blood pressure effects and vascular remodeling

Do not increase the quantity or frequency

Most strikingly, multiple trials have now shown that GLP-1 agonists can lead to the resolution of MASH, a severe form of fatty liver disease, without worsening of liver fibrosis, which is a common adverse outcome seen with some current medications

Adipose tissue strongly enhances GIP secretion [19] and GIP levels are high in obese people with T2DM

As insulin resistance improves and weight decreases, many women notice: More regular menstrual cycles Improved or restored ovulation Reduced acne and excess hair growth Better energy and mood balance Lower risk of developing Type 2 diabetes This approach aligns with comprehensive OBGYN care that treats interconnected hormonal and metabolic factors together

Avoid overly aggressive treatment of hypoglycemia