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Dosing Schedule, Storage, and Handling Instructions Retatrutide is investigated as a once-weekly subcutaneous injection, starting at 2 mg and escalating incrementally to up to 12 mg

Instead, continue with your usual dosage as prescribed by your healthcare provider

However, if you move your dose earlier (shortening the gap between shots), you might have a slightly higher concentration of the drug in your system, which could lead to temporary nausea or fatigue

Kline most patients get started within 24 hours

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The study period was October 2018 to March 2023, average follow-up was 3.3 years, and all participants had a body mass index of at least 27 kilograms per square meter [kg/m 2 ])