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We observed Cys15, 48, and 170 as NAPQI target sites in GSTP1

The model shows that overexpression of genes on chromosome 21 and an increase in oxidative stress can explain the metabolic profile of Down syndrome

doi: 10.1038/s42255-023-00930-8 150 WangYHChangDYZhaoYYTangSCZhaoMHChenM

5 This led to the suggestion that polyphenol-mediated decrease in intrinsic GSH or efflux can sensitise lymphoid cancer cell lines to topoisomerase II inhibitors, which results in the synergistic and additive induction of apoptosis

Andropause Male menopause is referred to as andropause

Quadrilatero J, Hoffman-Goetz L: N-Acetyl-L-cysteine prevents exercise-induced intestinal lymphocyte apoptosis by maintaining intracellular glutathione levels and reducing mitochondrial membrane depolarization