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Systemic deficiency of glutathione in cystic fibrosis

Medications including metformin, proton pump inhibitors, and H2-receptor antagonists may reduce absorption of B12, potentially prolonging the time to clinical improvement

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"Saccade and cognitive impairment associated with kava intoxication"

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These include lower GABA concentration in OCC (72, 75, 144), dorsomedial/dorsal anterolateral PFC (71) and ACC of depressed subjects (137, 139, 142, 143, 155)