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In Vitro PBMC Infection and Treatment Following the PBMCs resting overnight, they were infected with either the Erdman strain of M

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Topiramate is a carbonic anhydrase inhibitor, which means it blocks a specific enzyme in the body

Given that various chemical substances have been identified as neurotransmitters/neuromodulators in mammals, eliciting long-distance ionic responses that effectively mediate neurotransmission, identification of more systematic signaling molecules in the future would offer new insights into the complex systemic defense signaling in plants

For differential expression analysis, the R package limma (v.3.54.2) was used to identify differentially expressed proteins

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