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In the original study, data were collected from 1426 children (701 boys) in the age range of 1116 years, randomly selected from all the six Governorates of Kuwait, utilizing multi-stage random cluster sampling methods with a probability proportional to the size of each governorate

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Other gut-derived targets for pharmacotherapy Although GIP and GLP-1 have been identified as the most important humoral mediators of the incretin effect, other gut-derived factors are also involved in glucose and energy homoeostasis and may therefore qualify as future therapeutic targets [13] (Fig