10.2147/DDDT.S386974 44 NiuY.ZhouW.NieZ.ShinK.CuiX
de Groot S, Vreeswijk MP, Welters MJ, Gravesteijn G, Boei JJ, Jochems A,
Covers the Russo 2013 decreased-HGF/GABA-in-OCD paper (the single most direct mechanistic link between Dihexas Read the full review Psychiatry & Mood Disorders 21 May 2026 Dihexa for Bipolar Disorder: Lithium Neuroprotection, BDNF/HGF, Caplyta & the 2026 UK Review Can Dihexa help bipolar disorder, bipolar depression or bipolar cognitive impairment
Because there is not enough high-quality human evidence to support routine clinical use and they are not currently approved for use in Humans by Health Canada or the FDA
GHK-Cu adds the collagen and anti-inflammatory layer
Hence, Figure 3 shows all of the ACP isoenzymes expressed in the gut as potential catalysts of ThMP hydrolysis