A key question many people now have is: Can GLP-1 weight loss drugs help with migraines, or are they strictly weight-loss tools
Potentiation of GLP-1 action through receptor agonists has demonstrated efficacy in treating metabolic disease (61, 62)
The HbA1c reduction, as with other antihyperglycaemic agents depends largely on the patient population studied, the baseline glycaemic situation at the beginning of the observation and the concomitant therapy, including life-style intervention (12, 19, 21, 22)
Am J Physiol 251(6 Pt 2):H1106H1110
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Reduced Quantal Size : Under repeated amphetamine exposure, the combination of vesicular NE displacement (via proton gradient collapse) and VMAT2 blockade prevents newly recycled or recruited vesicles from being effectively refilled with NE (Sulzer et al, 1995