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AOD 9604 causes mild, transient nausea at most
HMGB1 translocation from nucleus to the cytoplasm of renal tubular cells induces ferroptosis by binding ACSL4 after renal I/R injury, and inhibition the nuclear cytoplasmic translocation of HMGB1 could inhibit ferroptosis and renal I/R injury
The intention is also to allow the peptide to come directly in contact with the gut lining
& Sipkins, D
M., Boersema, M
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