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In vitro hepatic models suggested that flavonoids and sulfur-containing compounds in garlic supplements might interfere with the activity of efflux drug transporters of the ATP-binding cassette (ABC) family, including P-glycoprotein, multidrug resistance protein (MRP), and breast cancer-resistance protein (BCRP), which function as ATP-dependent efflux pumps that actively regulate the excretion of a number of drugs limiting their systemic bioavailability
It flags that protein as a dangerous enemy
Patients with severe deficiency or certain health problems might need a stronger initial treatment
First, however, we need to clarify the basic terms
Rewires Substrate Use Cells shift to preferential glucose and fatty-acid oxidation, restoring metabolic flexibility
Canepa L, Ferraris AM, Miglino M, Gaetani GF
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