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Tracy Norfleet, MD, FACP, advises: "Injection site may be infected if you notice redness, warmth, or tenderness or swelling in the area, and it keeps getting worse or lasts more than 1 to 2 days." Here are specific signs that should prompt you to consult your doctor: Pus or discharge coming from the injection site Warmth spreading beyond the immediate area Red streaking extending outward from the injection site Redness or swelling larger than 2 inches in diameter Hardened lumps that dont go away, suggesting a possible infection Severe pain that disrupts your daily activities Reactions lasting more than a week Unusual skin discoloration Fever accompanied by chills New lumps or swelling in your neck, especially with hoarseness or difficulty swallowing If any of these symptoms appear, dont delay contacting your healthcare provider

Bullock BP, Heller RS, Habener JF: Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor

ClinicalTrials.gov Wilding JPH, Batterham RL, Calanna S, et al

Every cell reflects the cited sources

Segmentation and surface reconstruction

However, further activity studies of NAPQI-modified GSTA1 are needed to investigate this