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Phase II Detoxification in the Liver Glutathione transferases (GST) conjugate GSH directly to endogenous and exogenous electrophilic compounds, including xenobiotics, carcinogens, and heavy metals
To control the concentrations of H2O2, the enzymatic reaction of GPX uses GSH, which acts as a reducer
Furthermore, it has also been reported that siRNA has been successfully delivered in high EpCAM expressing MCF-7 and WERI-Rb1 tumor cells by using EpCAM decorated PEI nanosystem, resulting in significant EpCAM silencing with the decrease in tumor cell proliferation [235]
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
Glutathione, which is your bodys strongest natural antioxidant, can help reduce oxidative stress and neutralize the damage from free radicals
Glutathione promotes immune system balance and tolerance, preventing excessive immune activation that can result in allergies, autoimmune diseases, or chronic inflammation
