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Research focus: Cellular senescence, stress-induced aging models, and senescence-associated secretory phenotype (SASP) biology

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Data are presented as the mean SD of three or four biological replicates in three or four independent samples

It is also characterized by iron overload and downregulated expression of anti-oxidant proteins, including glutathione peroxidases (GSH-Px), superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase 4 (GPX4)

Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells