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Tirzepatide, the first dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) RA approved for both conditions, has paved the way for next-generation incretin-based therapies

Lower levels of IGF-1 and growth hormone in older adults have been linked with (5, 14): increased fat mass increased cardiovascular risk decreased muscle mass and strength lower cognitive function lower bone density limited joint mobility Several of these traits are seen in frail older adults

The neutrophil-to-lymphocyte ratio (NLR) increases during aging

GLP-1RAs may help alleviate myocardial damage linked to chronic hyperglycaemia

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Moreover, L-carnitine has been found to aid in yet another crucial process - the release of triglycerides into the bloodstream