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Potential signs suggesting nutritional review may be needed: Excessive fatigue or weakness beyond expected treatment effects Noticeable decline in muscle strength or physical function Persistent hunger despite adequate calorie intake Difficulty meeting protein targets consistently Note that these signs are non-specific and may have multiple causes

Avoid doses that exceed 121 milligrams per kilogram (or 2.2 pounds) of your body weight

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A healthcare provider must evaluate your overall health and history to decide if medication is right for you

Adv Exp Med Biol (2021) 1328:51322

This article examines the evidence surrounding Rybelsus and mood changes, explores how to recognise mental health concerns, and outlines what steps to take if you experience low mood whilst taking this medication